RNH1 antibody

Catalog No. ABIN7882167

This Mouse Monoclonal antibody specifically detects RNH1 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RNH1 antibody (ABIN7882167)

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RNH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4F3

Product Details anti-RNH1 Antibody

Purpose: RNH1 Antibody / Ribonuclease Inhibitor

Sequence: SLDIQSLDIQ CEELSDARWA ELLPLLQQCQ VVRLDD

Purification: Affinity purified

Immunogen: Amino acids SLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDD from the human protein were used as the immunogen for the RNH1 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the RNH1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RNH1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RNH1

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Alternative Name: RNH1

Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

UniProt: P13489