Recombinant RPS6KA3 antibody

Catalog No. ABIN7882175

The Rabbit Monoclonal anti-RPS6KA3 antibody (Clone 28R24) (ABIN7882175) specifically detects RPS6KA3 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant RPS6KA3 antibody (ABIN7882175)

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RPS6KA3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 28R24

Product Details anti-RPS6KA3 Antibody

Purpose: RSK2 Antibody / RPS6KA3 / Ribosomal protein S6 kinase alpha 3

Purification: Affinity chromatography

Immunogen: A synthetic peptide derived from human RSK2 / RPS6KA3 was used as the immunogen for the RSK2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RSK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the RSK2 antibody at -20oC.

Target Details for RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Alternative Name: RSK2

Background: Ribosomal protein S6 kinase alpha 3 (RPS6KA3, RSK2) is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. [UniProt]

UniProt: P51812

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades