SPTAN1 antibody

Catalog No. ABIN7882346

The Mouse Monoclonal anti-SPTAN1 antibody (Clone SPTAN1-3506) (ABIN7882346) specifically detects SPTAN1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for SPTAN1 antibody (ABIN7882346)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPTAN1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPTAN1-3506

Product Details anti-SPTAN1 Antibody

Purpose: Alpha Fodrin Antibody / Alpha II Spectrin / SPTAN1 / NEAS

Purification: Protein A/G affinity

Immunogen: A portion of amino acids2351-2475 was used as the immunogen for the Alpha Fodrin antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Alpha Fodrin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Alpha Fodrin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Alternative Name: Alpha Fodrin

Background: Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous II, a neuronal cytoskeleton protein.

UniProt: Q13813

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization