SF3B4 antibody

Catalog No. ABIN7882354

The Rabbit Polyclonal anti-SF3B4 antibody is suitable to detect SF3B4 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for SF3B4 antibody (ABIN7882354)

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SF3B4 Antibody

Purpose: SF3B4 Antibody / Splicing factor 3B subunit 4

Sequence: LDEKVSEPLL WELFLQA

Purification: Antigen affinity purified

Immunogen: Amino acids LDEKVSEPLLWELFLQA from the human protein were used as the immunogen for the SF3B4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SF3B4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SF3B4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SF3B4

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Alternative Name: SF3B4

Background: Splicing factor 3B subunit 4 is a protein that in humans is encoded by the SF3B4 gene. This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.

UniProt: Q15427