Stathmin 1 antibody

Catalog No. ABIN7882366

The Mouse Monoclonal anti-Stathmin 1 antibody is suitable to detect Stathmin 1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Stathmin 1 antibody (ABIN7882366)

Target: Stathmin 1 (STMN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: STMN1-8439

Product Details anti-Stathmin 1 Antibody

Purpose: Oncoprotein 18 Antibody / OP18 / Stathmin 1

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human Stathmin 1 protein was used as the immunogen for the Oncoprotein 18 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Oncoprotein 18 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Oncoprotein 18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Oncoprotein 18

Background: Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics