Stathmin 1 antibody

Catalog No. ABIN7882367

The Mouse Monoclonal anti-Stathmin 1 antibody (Clone STMN1-8437) (ABIN7882367) specifically detects Stathmin 1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Stathmin 1 antibody (ABIN7882367)

Target: Stathmin 1 (STMN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: STMN1-8437

Product Details anti-Stathmin 1 Antibody

Purpose: Stathmin 1 Antibody / STMN1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human STMN1 protein was used as the immunogen for the Stathmin 1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Stathmin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Stathmin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background: Stathmin 1 (Oncoprotein 18, STM1, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of the protein are observed, and it is expressed as two different isoforms. Stathmin 1 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. It is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics