Stathmin 1 antibody

Catalog No. ABIN7882368

This Mouse Monoclonal antibody specifically detects Stathmin 1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Stathmin 1 antibody (ABIN7882368)

Target: Stathmin 1 (STMN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: STMN1-8437

Product Details anti-Stathmin 1 Antibody

Purpose: Stathmin 1 Antibody / STMN1

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human STMN1 protein was used as the immunogen for the Stathmin 1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Stathmin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Stathmin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background: Stathmin 1 (Oncoprotein 18, STM1, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of the protein are observed, and it is expressed as two different isoforms. Stathmin 1 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. It is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics