SULT1E1 antibody

Catalog No. ABIN7882385

The Mouse Monoclonal anti-SULT1E1 antibody (Clone CPTC-SULT1E1-1) (ABIN7882385) specifically detects SULT1E1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SULT1E1 antibody (ABIN7882385)

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SULT1E1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CPTC-SULT1E1-1

Product Details anti-SULT1E1 Antibody

Purpose: SULT1E1 Antibody / Estrogen Sulfotransferase (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the SULT1E1 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the SULT1E1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the SULT1E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Alternative Name: SULT1E1

Background: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis