TLR9 antibody

Catalog No. ABIN7882502

The Rabbit Polyclonal anti-TLR9 antibody (ABIN7882502) specifically detects TLR9 in WB and IHC (p). The antibody is reactive with Human and Rat samples.

Quick Overview for TLR9 antibody (ABIN7882502)

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TLR9 Antibody

Purpose: TLR9 Antibody

Sequence: SRKTLFVLAH TDRVSGLLRA SFLLAQQRLL EDRKD

Purification: Antigen affinity purified

Immunogen: Amino acids SRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKD were used as the immunogen for the TLR9 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TLR9 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TLR9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TLR9

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Alternative Name: TLR9

Background: Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

UniProt: Q9NR96

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades