TPT1 antibody

Catalog No. ABIN7882603

The Rabbit Monoclonal anti-TPT1 antibody is suitable to detect TPT1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for TPT1 antibody (ABIN7882603)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TPT1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ACDD-20

Product Details anti-TPT1 Antibody

Purpose: TCTP Antibody / TPT1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human TCTP / TPT1 was used as the immunogen for the TCTP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TCTP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the TCTP antibody at -20oC.

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TCTP

Background: The TPT1 gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [RefSeq]

UniProt: P13693

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling