VEGF antibody

Catalog No. ABIN7882663

The Mouse Monoclonal anti-VEGF antibody is suitable to detect VEGF in samples from Human. It has been validated for IF.

Quick Overview for VEGF antibody (ABIN7882663)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VEGF antibody is un-conjugated

Application: Immunofluorescence (IF)

Clone: VG76e

Product Details anti-VEGF Antibody

Purpose: VEGF Antibody / Vascular Endothelial Growth Factor

Purification: Protein A/G affinity

Immunogen: Human VEGF189 recombinant protein was used as the immunogen for the VEGF antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the VEGF antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the VEGF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Alternative Name: VEGF

Background: This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet-derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

UniProt: P15692