NR1D1 antibody (pSer55, pSer59)
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- Target See all NR1D1 Antibodies
- NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))
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Binding Specificity
- pSer55, pSer59
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR1D1 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- These phosphorylation sites are homologous among the listed cross-reactive species.
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Cow,Sheep
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human REV-ERB alpha around the phosphorylation site of Ser55/59
- Isotype
- IgG
- Top Product
- Discover our top product NR1D1 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))
- Alternative Name
- NR1D1 + (NR1D1 Products)
- Synonyms
- MGC82865 antibody, MGC82881 antibody, Eip75B antibody, EAR1 antibody, THRA1 antibody, THRAL antibody, ear-1 antibody, hRev antibody, A530070C09Rik antibody, R75201 antibody, REV-ERBAALPHA antibody, nuclear receptor subfamily 1 group D member 1 L homeolog antibody, nuclear receptor subfamily 1, group d, member 1 antibody, nuclear receptor subfamily 1 group D member 1 antibody, nuclear receptor subfamily 1, group D, member 1 antibody, nr1d1.L antibody, nr1d1 antibody, NR1D1 antibody, Nr1d1 antibody
- Background
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Synonyms: EAR1, hRev, THRA1, THRAL, ear-1, Nuclear receptor subfamily 1 group D member 1, Rev-erbA-alpha, V-erbA-related protein 1, NR1D1
Background: This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]
- Gene ID
- 9572
- UniProt
- P20393
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha
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