TPT1 antibody (pSer46)

Catalog No. ABIN746093

The Rabbit Polyclonal anti-TPT1 antibody has been validated for ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect TPT1 in samples from Mouse.

Quick Overview for TPT1 antibody (pSer46) (ABIN746093)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPT1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TPT1 Antibody

Binding Specificity: pSer46

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human TCTP around the phosphorylation site of Ser46

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TCTP

Background:

Synonyms: Fortilin, Histamine-releasing factor, p02, p23, TPT1, translationally controlled tumor protein, tumor protein translationally-controlled 1, TCTP_HUMAN.

Background: TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM).

Gene ID: 7178

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling