TPT1 antibody (pSer46) (HRP)

Catalog No. ABIN746102

The Rabbit Polyclonal anti-TPT1 antibody is suitable to detect TPT1 in samples from Human. It has been validated for IHC (p) and IHC (fro).

Quick Overview for TPT1 antibody (pSer46) (HRP) (ABIN746102)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPT1 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TPT1 Antibody (HRP)

Binding Specificity: pSer46

Purpose: Phospho-TCTP (Ser46) Polyclonal Antibody, HRP Conjugated

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse,Rabbit,GuineaPig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human TCTP around the phosphorylation site of Ser46

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TCTP

Background:

Synonyms: Fortilin, Histamine-releasing factor, p02, p23, TPT1, translationally controlled tumor protein, tumor protein translationally-controlled 1, TCTP_HUMAN.

Background: TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM).

Gene ID: 7178

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling