ENOS antibody

Catalog No. ABIN969097

This Mouse Monoclonal antibody specifically detects ENOS in ELISA and IHC. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for ENOS antibody (ABIN969097)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ENOS antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 6H2

Product Details anti-ENOS Antibody

Purpose: eNOS Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human eNOS expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ENOS antibody (ABIN969097)

Moreno: "Genetic polymorphisms and haplotypes of eNOS in breast cancer." in: Breast cancer research and treatment, Vol. 109, Issue 1, pp. 181-2, (2008) (PubMed).

Lahiri, Martin: "Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line." in: Oncology reports, Vol. 12, Issue 5, pp. 1007-11, (2004) (PubMed).

Target Details for ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Alternative Name: eNOS

Background: Endothelial nitric-oxide synthase (eNOS), also known as NOS3, it is an important enzyme in the cardiovascular system. It is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.

Molecular Weight: 133 kDa

Gene ID: 4846

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling