Recombinant ALKBH5 antibody

Catalog No. ABIN7938043

This Rabbit Monoclonal antibody specifically detects ALKBH5 in WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant ALKBH5 antibody (ABIN7938043)

Target: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ALKBH5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 2K9

Product Details anti-ALKBH5 Antibody

Purpose: ALKBH5 antibody (rAb), 100 μl (Clone 2K9)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the ALKBH5 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:50000 dilution IF: 1:250-1:1000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for ALKBH5

Target: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Alternative Name: ALKBH5

Background:

Background_Plain: ALKBH5 (ABH5 and OFOXD1) is a Dioxygenase that demethylates RNA by oxidative demethylation. It is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo.ALKBH5 is required for spermatogenesis. Two major isoforms for this target are located at a of MW 40-44 kDa and 52 kDa.

Aliases: AlkB Homolog 5, RNA Demethylase, Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 5, OFOXD1, ABH5

Molecular Weight: 57 kDa