Recombinant CDX2 antibody

Catalog No. ABIN7938091

This Rabbit Monoclonal antibody specifically detects CDX2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant CDX2 antibody (ABIN7938091)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDX2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3J1

Product Details anti-CDX2 Antibody

Purpose: CDX2 antibody (rAb), 100 μl (Clone 3J1)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the CDX2 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:5000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Alternative Name: CDX2

Background:

Background_Plain: CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and CDX2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.

Aliases: Caudal type homeobox 2

Molecular Weight: 34 kDa

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance