Recombinant HIC2 antibody

Catalog No. ABIN7938154

This Rabbit Monoclonal antibody specifically detects HIC2 in IF. It exhibits reactivity toward Human.

Quick Overview for Recombinant HIC2 antibody (ABIN7938154)

Target: HIC2 (Hypermethylated in Cancer 2 (HIC2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HIC2 antibody is un-conjugated

Application: Immunofluorescence (IF)

Clone: 230177E8

Product Details anti-HIC2 Antibody

Purpose: HIC2 antibody (rAb), 100 μg (Clone 230177E8)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the HIC2 fusion protein.

Isotype: IgG

Application Details

Application Notes: IF: 1:200-1:800 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for HIC2

Target: HIC2 (Hypermethylated in Cancer 2 (HIC2))

Alternative Name: HIC2

Background:

Background_Plain: HIC2 (hypermethylated in cancer 2) is a transcription factor related to the tumor suppressor HIC1, required for normal cardiac development and lost in distal variants of 22q11 Deletion Syndrome. HIC2 is also a POK family protein, and the amino acid sequence of its BTB/POZ and zinc-finger domains are like those of HIC1. Studies have shown that HIC2 plays a role in suppressing fetal genes for normal development of the heart and circulatory system, in embryogenesis.

Aliases: Hypermethylated in Cancer 2, HRG22, ZBTB30, ZNF907

Molecular Weight: 66 kDa