Recombinant IRF3 antibody

Catalog No. ABIN7938286

This Rabbit Monoclonal antibody specifically detects IRF3 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant IRF3 antibody (ABIN7938286)

Target: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IRF3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 2H6

Product Details anti-IRF3 Antibody

Purpose: IRF3 antibody (rAb), 100 μg (Clone 2H6)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the IRF3 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:2000-1:10000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for IRF3

Target: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Alternative Name: IRF3

Background:

Background_Plain: IRF3 (Interferon regulatory factor 3)is a member of the IRF family of transcription factors that include IRF1, IRF6 and IRF7. IRF3 that has been phosphorylated at serine/threonine forms a complex with CREBBP and translocates to the nucleus to activate transcription of interferon-induced genes. IRF3 plays a critical role in the innate immune response against DNA and RNA viruses.

Aliases: Interferon Regulatory Factor 3

Molecular Weight: 47 kDa

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades