Recombinant NRF2 antibody

Catalog No. ABIN7938378

The Rabbit Monoclonal anti-NRF2 antibody (Clone 1I21) (ABIN7938378) specifically detects NRF2 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant NRF2 antibody (ABIN7938378)

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1I21

Product Details anti-NRF2 Antibody

Purpose: NRF2 antibody (rAb), 100 μl (Clone 1I21)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the NRF2 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:5000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Alternative Name: NRF2

Background:

Background_Plain: NRF2 (NF-E2-Related Factor 2) is a transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Aliases: NFE2L2

Molecular Weight: 68 kDa

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling