Recombinant RAN antibody

Catalog No. ABIN7938425

The Rabbit Monoclonal anti-RAN antibody is suitable to detect RAN in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Recombinant RAN antibody (ABIN7938425)

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RAN antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 230317F3

Product Details anti-RAN Antibody

Purpose: RAN antibody (rAb), 100 μl (Clone 230317F3)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the RAN fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:5000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for RAN

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Alternative Name: RAN

Background:

Background_Plain: RAN is also named ARA24, Ras-like protein TC4 and GTPase Ran, and belongs to the small GTPase superfamily family and the RAN family. GTPase RAN switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation.

Aliases: Ras-related nuclear protein

Molecular Weight: 25 kDa

Pathways: Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus