Recombinant SIRT5 antibody

Catalog No. ABIN7938490

This Rabbit Monoclonal antibody specifically detects SIRT5 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant SIRT5 antibody (ABIN7938490)

Target: SIRT5 (Sirtuin 5 (SIRT5))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SIRT5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 7L20

Product Details anti-SIRT5 Antibody

Purpose: SIRT5 antibody (rAb), 100 μg (Clone 7L20)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the SIRT5 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:2000-1:10000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Alternative Name: SIRT5

Background:

Background_Plain: SIRT5, a member fo sirtuin family that is a mitochondrial matrix NAD(+)-dependent deacetylase and mono-ADP-ribosyltransferases. Sirtuins play an important role in various cellular processes, such as aging, gene silencing and metabolism. SIRT5 mainly locates in cytoplasm. It is an efficient protein lysine desuccinylase and demalonylase. During prolonged fasting, it can activate CPS1, the committed and regulated enzyme of the urea cycle, and this contributes to the regulation of blood ammonia levels.

Aliases: SIRT-5, Sirtuin 5, SIR2L5, SIR2-Like Protein 5

Molecular Weight: 34 kDa

Pathways: SARS-CoV-2 Protein Interactome