Recombinant YY1 antibody

Catalog No. ABIN7938554

The Rabbit Monoclonal anti-YY1 antibody is suitable to detect YY1 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for Recombinant YY1 antibody (ABIN7938554)

Target: YY1 (YY1 Transcription Factor (YY1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This YY1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1B5

Product Details anti-YY1 Antibody

Purpose: YY1 antibody (rAb), 100 μl (Clone 1B5)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the YY1 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:8000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for YY1

Target: YY1 (YY1 Transcription Factor (YY1))

Alternative Name: YY1

Background:

Background_Plain: YY1 (Yin Yang 1) is a transcription factor that belongs to the GLI-Kruppel class of zinc finger transcription factors and is ubiquitously expressed. YY1 is known to have a fundamental role in normal biologic processes such as embryogenesis, differentiation, replication and cellular proliferation. YY1 exerts its effects on genes involved in these processes via its ability to initiate, activate or repress transcription depending upon the context in which it binds. Since expression and function of YY1 are known to be intimately associated with progression through phases of the cell cycle, the physiologic significance of YY1 activity has been applied to models of tumor biology. It can repress and activate a number of gene promoters and direct histone deacetylases (HDACs) and histone acetyltransferases (HATs).

Aliases: DELTA, NF-E1, UCRBP, INO80S, YIN-YANG-1

Molecular Weight: 45 kDa