OXCT1 antibody (AA 35-309) (Biotin)

Catalog No. ABIN7964922

The Biotin-conjugated Rabbit Polyclonal anti-OXCT1 antibody (ABIN7964922) specifically detects OXCT1 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for OXCT1 antibody (AA 35-309) (Biotin) (ABIN7964922)

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXCT1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-OXCT1 Antibody (Biotin)

Binding Specificity: AA 35-309

Purpose: Anti-OXCT1/SCOT Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OXCT1/SCOT recombinant protein (Position: S35-A309).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OXCT1

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Alternative Name: OXCT1

Background:

Background: 3-oxoacid CoA-transferase 1 (OXCT1) is an enzyme that in humans is encoded by the OXCT1 gene. It is also known as succinyl-CoA-3-oxaloacid CoA transferase (SCOT). This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.

Gene Full Name: 3-oxoacid CoA-transferase 1

Gene ID: 5019

UniProt: P55809

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis