MTR antibody (AA 880-1095) (HRP)

Catalog No. ABIN7965105

The HRP-conjugated Rabbit Polyclonal anti-MTR antibody (ABIN7965105) specifically detects MTR in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MTR antibody (AA 880-1095) (HRP) (ABIN7965105)

Target: MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase (MTR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTR antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MTR Antibody (HRP)

Binding Specificity: AA 880-1095

Purpose: Anti-MTR Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MTR recombinant protein (Position: V880-D1095).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MTR

Target: MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase (MTR))

Alternative Name: MTR

Background:

Background: Methionine synthase also known as MS, MeSe, MetH is responsible for the regeneration of methionine from homocysteine. In humans it is encoded by the MTR gene (5-methyltetrahydrofolate-homocysteine methyltransferase). It is mapped to 1q43. This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Full Name: 5-methyltetrahydrofolate-homocysteine methyltransferase

Gene ID: 4548

UniProt: Q99707

Pathways: Methionine Biosynthetic Process