MTRR antibody (AA 7-698) (PE)

Catalog No. ABIN7965118

This Rabbit Polyclonal antibody specifically detects MTRR in ELISA, WB, IHC, FACS, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MTRR antibody (AA 7-698) (PE) (ABIN7965118)

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTRR antibody is conjugated to PE

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-MTRR Antibody (PE)

Binding Specificity: AA 7-698

Purpose: Anti-MTRR Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MTRRshares 78.3%,79% amino acid (aa) sequence identity with mouse,rat MTRR,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MTRR recombinant protein (Position: L7-S698). Human MTRRshares 78.3% and 79% amino acid (aa) sequence identity with mouse and rat MTRR, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MTRR

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Alternative Name: MTRR

Background:

Background: This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Gene ID: 4552

UniProt: Q9UBK8

Pathways: Methionine Biosynthetic Process