MTRR antibody (AA 7-698)

Catalog No. ABIN7965120

The Rabbit Polyclonal anti-MTRR antibody (ABIN7965120) specifically detects MTRR in ELISA, WB, IHC, FACS, IF and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MTRR antibody (AA 7-698) (ABIN7965120)

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTRR antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Grade: Carrier-free

Product Details anti-MTRR Antibody

Binding Specificity: AA 7-698

Purpose: Anti-MTRR Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MTRRshares 78.3%,79% amino acid (aa) sequence identity with mouse,rat MTRR,respectively.

Characteristics: Anti-MTRR Antibody. Tested in WB, IHC, IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MTRR recombinant protein (Position: L7-S698). Human MTRRshares 78.3% and 79% amino acid (aa) sequence identity with mouse and rat MTRR, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MTRR

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Alternative Name: MTRR

Background:

Background: This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Molecular Weight: 78 kDa

Gene ID: 4552

UniProt: Q9UBK8

Pathways: Methionine Biosynthetic Process