AKAP8 antibody (AA 380-546) (APC)

Catalog No. ABIN7965304

This Rabbit Polyclonal antibody specifically detects AKAP8 in FACS. It exhibits reactivity toward Human.

Quick Overview for AKAP8 antibody (AA 380-546) (APC) (ABIN7965304)

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP8 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-AKAP8 Antibody (APC)

Binding Specificity: AA 380-546

Purpose: Anti-AKAP 95/AKAP8 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AKAP 95/AKAP8 recombinant protein (Position: T380-F546).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AKAP8

Target: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Alternative Name: AKAP8

Background:

Background: A-kinase anchor protein 8 is an enzyme that, in humans, is encoded by the AKAP8 gene. This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.

Gene Full Name: A-kinase anchoring protein 8

Gene ID: 10270

UniProt: O43823

Pathways: SARS-CoV-2 Protein Interactome