ACSL1 antibody (AA 604-698) (Fluoro647)

Catalog No. ABIN7966120

This Rabbit Polyclonal antibody specifically detects ACSL1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ACSL1 antibody (AA 604-698) (Fluoro647) (ABIN7966120)

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACSL1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-ACSL1 Antibody (Fluoro647)

Binding Specificity: AA 604-698

Purpose: Anti-ACSL1 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human ACSL1 recombinant protein (Position: D604-V698). Human ACSL1 shares 81.1%,86.3% amino acid (aa) sequence identity with mouse,rat ACSL1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ACSL1 recombinant protein (Position: D604-V698). Human ACSL1 shares 81.1% and 86.3% amino acid (aa) sequence identity with mouse and rat ACSL1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ACSL1

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Alternative Name: ACSL1

Background:

Background: Long-chain-fatty-acid-CoA ligase 1 is an enzyme that in humans is encoded by the ACSL1 gene. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. This specific protein is most commonly found in mitochondria and peroxisomes.

Gene Full Name: acyl-CoA synthetase long chain family member 1

Gene ID: 2180

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha