Acsl3 antibody (AA 12-224) (Cy3)

Catalog No. ABIN7966123

This Rabbit Polyclonal antibody specifically detects Acsl3 in FACS. It exhibits reactivity toward Human.

Quick Overview for Acsl3 antibody (AA 12-224) (Cy3) (ABIN7966123)

Target: Acsl3 (Acyl-CoA Synthetase Long-Chain Family Member 3 (Acsl3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acsl3 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-Acsl3 Antibody (Cy3)

Binding Specificity: AA 12-224

Purpose: Anti-ACSL3 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human ACSL3 shares 91.1%,90.1% amino acid (aa) sequence identity with mouse,rat ACSL3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ACSL3 recombinant protein (Position: M12-I224). Human ACSL3 shares 91.1% and 90.1% amino acid (aa) sequence identity with mouse and rat ACSL3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Acsl3

Target: Acsl3 (Acyl-CoA Synthetase Long-Chain Family Member 3 (Acsl3))

Alternative Name: ACSL3

Background:

Background: Long-chain-fatty-acid-CoA ligase 3 is an enzyme that in humans is encoded by the ACSL3 gene. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92 % identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.

Gene Full Name: acyl-CoA synthetase long chain family member 3

Gene ID: 2181

UniProt: O95573

Pathways: SARS-CoV-2 Protein Interactome