ACSL4 antibody (AA 36-237) (Fluoro488)

Catalog No. ABIN7966157

The Rabbit Polyclonal anti-ACSL4 antibody is suitable to detect ACSL4 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for ACSL4 antibody (AA 36-237) (Fluoro488) (ABIN7966157)

Target: ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACSL4 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-ACSL4 Antibody (Fluoro488)

Binding Specificity: AA 36-237

Purpose: Anti-FACL4/ACSL4 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FACL4/ACSL4 recombinant protein (Position: A36-E237).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ACSL4

Target: ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

Alternative Name: ACSL4

Background:

Background: Long-chain-fatty-acid-CoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. It is mapped to Xq23. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants.

Gene Full Name: acyl-CoA synthetase long chain family member 4

Gene ID: 2182

UniProt: O60488