ADAM22 antibody (AA 223-829) (APC)

Catalog No. ABIN7966338

The APC-conjugated Rabbit Polyclonal anti-ADAM22 antibody (ABIN7966338) specifically detects ADAM22 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ADAM22 antibody (AA 223-829) (APC) (ABIN7966338)

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM22 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-ADAM22 Antibody (APC)

Binding Specificity: AA 223-829

Purpose: Anti-ADAM22 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ADAM22 recombinant protein (Position: S223-R829).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ADAM22

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Alternative Name: ADAM22

Background:

Background: Disintegrin and metalloproteinase domain-containing protein 22 also known as ADAM22 is an enzyme that in humans is encoded by the ADAM22 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

Gene Full Name: ADAM metallopeptidase domain 22

Gene ID: 53616

UniProt: Q9P0K1