AMPD1 antibody (AA 5-747) (Fluoro550)

Catalog No. ABIN7966730

The Rabbit Polyclonal anti-AMPD1 antibody is suitable to detect AMPD1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for AMPD1 antibody (AA 5-747) (Fluoro550) (ABIN7966730)

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMPD1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-AMPD1 Antibody (Fluoro550)

Binding Specificity: AA 5-747

Purpose: Anti-AMPD1 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human AMPD1 shares 92.7% amino acid (aa) sequence identity with both mouse,rat AMPD1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AMPD1 recombinant protein (Position: K5-E747). Human AMPD1 shares 92.7% amino acid (aa) sequence identity with both mouse and rat AMPD1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AMPD1

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Alternative Name: AMPD1

Background:

Background: AMP deaminase 1 is an enzyme that in humans is encoded by the AMPD1 gene. Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Gene Full Name: adenosine monophosphate deaminase 1

Gene ID: 270

UniProt: P23109