AHCY antibody (AA 112-432) (APC)

Catalog No. ABIN7966745

The Rabbit Polyclonal anti-AHCY antibody is suitable to detect AHCY in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for AHCY antibody (AA 112-432) (APC) (ABIN7966745)

Target: AHCY (Adenosylhomocysteinase (AHCY))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHCY antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-AHCY Antibody (APC)

Binding Specificity: AA 112-432

Purpose: Anti-AHCY Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AHCY recombinant protein (Position: W112-Y432).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AHCY

Target: AHCY (Adenosylhomocysteinase (AHCY))

Alternative Name: AHCY

Background:

Background: S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: adenosylhomocysteinase

Gene ID: 191

UniProt: P23526