AHCY antibody (AA 112-432)

Catalog No. ABIN7966748

The Rabbit Polyclonal anti-AHCY antibody is suitable to detect AHCY in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for AHCY antibody (AA 112-432) (ABIN7966748)

Target: AHCY (Adenosylhomocysteinase (AHCY))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHCY antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-AHCY Antibody

Binding Specificity: AA 112-432

Purpose: Anti-AHCY Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-AHCY Antibody. Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AHCY recombinant protein (Position: W112-Y432).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat ELISA, 0.1-0.5 μg/m, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AHCY

Target: AHCY (Adenosylhomocysteinase (AHCY))

Alternative Name: AHCY

Background:

Background: S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: adenosylhomocysteinase

Molecular Weight: 45-48 kDa

Gene ID: 191

UniProt: P23526