ARL6IP6 antibody (Middle Region) (FITC)

Catalog No. ABIN7966985

The Rabbit Polyclonal anti-ARL6IP6 antibody is suitable to detect ARL6IP6 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ARL6IP6 antibody (Middle Region) (FITC) (ABIN7966985)

Target: ARL6IP6 (ADP-Ribosylation-Like Factor 6 Interacting Protein 6 (ARL6IP6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL6IP6 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-ARL6IP6 Antibody (FITC)

Binding Specificity: Middle Region

Purpose: Anti-ARL6IP6 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ARL6IP6, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ARL6IP6

Target: ARL6IP6 (ADP-Ribosylation-Like Factor 6 Interacting Protein 6 (ARL6IP6))

Alternative Name: ARL6IP6

Background:

Background: ADP ribosylation factor like GTPase 6 interacting protein 6 is a protein that in the humans is encoded by the ARL6IP6 gene. ARL6IP6 (ADP-ribosylation-like factor 6 interacting protein 6), also known as PFAAP1 (phosphonoformate immuno-associated protein 1), is a 226 amino acid multi-pass membrane protein that belongs to the ARL6IP6 family and is encoded by a gene that maps to human chromosome 2q23.3. A 2q23.3 novel microdeletion involving seven genes, including ARL6IP6, is linked to a proposed 2q23q24 microdeletion syndrome. Additional chromosome 2q deletions, which also include ARL6IP6, are linked to autism, developmental delays and communication impairment. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Gene Full Name: ARF like GTPase 6 interacting protein 6

Gene ID: 151188

UniProt: Q8N6S5

Pathways: SARS-CoV-2 Protein Interactome