AKR7A2 antibody (AA 294-359) (Fluoro647)

Catalog No. ABIN7967209

This Rabbit Polyclonal antibody specifically detects AKR7A2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AKR7A2 antibody (AA 294-359) (Fluoro647) (ABIN7967209)

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR7A2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-AKR7A2 Antibody (Fluoro647)

Binding Specificity: AA 294-359

Purpose: Anti-AKR7A2 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AKR7A2 recombinant protein (Position: A294-R359).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AKR7A2

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Alternative Name: AKR7A2

Background:

Background: Aflatoxin B1 aldehyde reductase member 2 is an enzyme that in humans is encoded by the AKR7A2 gene. It is mapped to 1p36.13. The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Gene Full Name: aldo-keto reductase family 7 member A2

Gene ID: 8574

UniProt: O43488