AGRP antibody (AA 82-131) (APC)

Catalog No. ABIN7967218

This Rabbit Polyclonal antibody specifically detects AGRP in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AGRP antibody (AA 82-131) (APC) (ABIN7967218)

Target: AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGRP antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-AGRP Antibody (APC)

Binding Specificity: AA 82-131

Purpose: Anti-AGRP Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse AGRP recombinant protein (Position: S82-T131).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AGRP

Target: AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

Alternative Name: Agrp

Background:

Background: Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

Gene Full Name: agouti related neuropeptide

Gene ID: 11604

UniProt: P56473

Pathways: Feeding Behaviour, Photoperiodism