ALDH1A2 antibody (AA 1-318) (APC)

Catalog No. ABIN7967416

This Rabbit Polyclonal antibody specifically detects ALDH1A2 in FACS. It exhibits reactivity toward Human.

Quick Overview for ALDH1A2 antibody (AA 1-318) (APC) (ABIN7967416)

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-ALDH1A2 Antibody (APC)

Binding Specificity: AA 1-318

Purpose: Anti-ALDH1A2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ALDH1A2 recombinant protein (Position: M1-Q318).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ALDH1A2

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Alternative Name: ALDH1A2

Background:

Background: Aldehyde dehydrogenase 1 family, member A2, also known as ALDH1A2 or retinaldehyde dehydrogenase 2 (RALDH2), is an enzyme that in humans is encoded by the ALDH1A2 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Gene Full Name: aldehyde dehydrogenase 1 family member A2

Gene ID: 8854

UniProt: O94788

Pathways: Retinoic Acid Receptor Signaling Pathway