ALKBH1 antibody (C-Term) (APC)

Catalog No. ABIN7967779

This Rabbit Polyclonal antibody specifically detects ALKBH1 in FACS. It exhibits reactivity toward Human.

Quick Overview for ALKBH1 antibody (C-Term) (APC) (ABIN7967779)

Target: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-ALKBH1 Antibody (APC)

Binding Specificity: C-Term

Purpose: Anti-ALKBH1 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ALKBH1, which shares 81.3% and 84.4% amino acid (aa) sequence identity with mouse and rat ALKBH1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ALKBH1

Target: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Alternative Name: ALKBH1

Background:

Background: Nucleic acid dioxygenase ALKBH1 is an enzyme that in humans is encoded by the ALKBH1 gene. It is mapped to 14q24.3. This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.

Gene Full Name: alkB homolog 1, histone H2A dioxygenase

Gene ID: 8846

UniProt: Q13686

Pathways: DNA Damage Repair