alpha 2 Antiplasmin antibody (AA 461-491) (HRP)

Catalog No. ABIN7967976

The HRP-conjugated Rabbit Polyclonal anti-alpha 2 Antiplasmin antibody (ABIN7967976) specifically detects alpha 2 Antiplasmin in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for alpha 2 Antiplasmin antibody (AA 461-491) (HRP) (ABIN7967976)

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 2 Antiplasmin antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-alpha 2 Antiplasmin Antibody (HRP)

Binding Specificity: AA 461-491

Purpose: Anti-Alpha 2 Antiplasmin/SERPINF2 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Alpha 2 Antiplasmin/SERPINF2 recombinant protein (Position: K461-K491).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Alternative Name: SERPINF2

Background:

Background: Alpha 2-antiplasmin (or α2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin. Plasmin is an important enzyme that participates in fibrinolysis and degradation of various other proteins. This protein is encoded by the SERPINF2 gene. This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: serpin family F member 2

Gene ID: 5345

UniProt: P08697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones