AASS antibody (AA 37-865) (HRP)

Catalog No. ABIN7968086

The Rabbit Polyclonal anti-AASS antibody is suitable to detect AASS in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for AASS antibody (AA 37-865) (HRP) (ABIN7968086)

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AASS antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-AASS Antibody (HRP)

Binding Specificity: AA 37-865

Purpose: Anti-AASS Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AASS recombinant protein (Position: E37-N865).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AASS

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Alternative Name: AASS

Background:

Background: Alpha-aminoadipic semialdehyde synthase is an enzyme encoded by the AASS gene in humans and is involved in their major lysine degradation pathway. This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

Gene Full Name: aminoadipate-semialdehyde synthase

Gene ID: 10157

UniProt: Q9UDR5

Pathways: SARS-CoV-2 Protein Interactome