APC1 antibody (AA 1-197) (Fluoro550)

Catalog No. ABIN7968347

The Rabbit Polyclonal anti-APC1 antibody is suitable to detect APC1 in samples from Human. It has been validated for FACS.

Quick Overview for APC1 antibody (AA 1-197) (Fluoro550) (ABIN7968347)

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APC1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-APC1 Antibody (Fluoro550)

Binding Specificity: AA 1-197

Purpose: Anti-APC1/ANAPC1 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human ANAPC1 shares 91.9% amino acid (aa) sequence identity with mouse ANAPC1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human APC1/ANAPC1 recombinant protein (Position: M1-E197). Human ANAPC1 shares 91.9% amino acid (aa) sequence identity with mouse ANAPC1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for APC1

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Alternative Name: ANAPC1

Background:

Background: Anaphase-promoting complex subunit 1 is an enzyme that in humans is encoded by the ANAPC1 gene. This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.

Gene Full Name: anaphase promoting complex subunit 1

Gene ID: 64682

UniProt: Q9H1A4