Annexin A2 antibody (N-Term) (HRP)

Catalog No. ABIN7968889

The Rabbit Polyclonal anti-Annexin A2 antibody is suitable to detect Annexin A2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for Annexin A2 antibody (N-Term) (HRP) (ABIN7968889)

Target: Annexin A2 (ANXA2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin A2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Annexin A2 Antibody (HRP)

Binding Specificity: N-Term

Purpose: Anti-Annexin A2/ANXA2 Antibody HRP Conjugated

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ANXA2, which shares 92.9% and 100% amino acid (aa) sequence identity with mouse and rat ANXA2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: ANXA2

Background:

Background: Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.

Gene Full Name: annexin A2

Gene ID: 302

UniProt: P07355

Pathways: S100 Proteins