Apelin antibody (C-Term) (FITC)

Catalog No. ABIN7969251

This Rabbit Polyclonal antibody specifically detects Apelin in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Apelin antibody (C-Term) (FITC) (ABIN7969251)

Target: Apelin (APLN)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apelin antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-Apelin Antibody (FITC)

Binding Specificity: C-Term

Purpose: Anti-Apelin/APLN Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related rat,mouse sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Apelin, identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Apelin

Target: Apelin (APLN)

Alternative Name: APLN

Background:

Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

Gene Full Name: apelin

Sequence Similarities: Belongs to the apelin family.

Gene ID: 8862

UniProt: Q9ULZ1

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour