Aprataxin antibody (AA 46-356) (Biotin)

Catalog No. ABIN7969543

The Rabbit Polyclonal anti-Aprataxin antibody is suitable to detect Aprataxin in samples from Human. It has been validated for ELISA, WB and IHC.

Quick Overview for Aprataxin antibody (AA 46-356) (Biotin) (ABIN7969543)

Target: Aprataxin (APTX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Aprataxin Antibody (Biotin)

Binding Specificity: AA 46-356

Purpose: Anti-APTX Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human APTXshares 84.8%,80.9% amino acid (aa) sequence identity with mouse,rat APTX,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human APTX recombinant protein (Position: E46-Q356). Human APTXshares 84.8% and 80.9% amino acid (aa) sequence identity with mouse and rat APTX, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: APTX

Background:

Background: This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.

Gene Full Name: aprataxin

Gene ID: 54840

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding