Aquaporin 10 antibody (C-Term) (Fluoro488)

Catalog No. ABIN7969622

The Fluoro488-conjugated Rabbit Polyclonal anti-Aquaporin 10 antibody (ABIN7969622) specifically detects Aquaporin 10 in FACS. The antibody is reactive with Human samples.

Quick Overview for Aquaporin 10 antibody (C-Term) (Fluoro488) (ABIN7969622)

Target: Aquaporin 10 (AQP10)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aquaporin 10 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Aquaporin 10 Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-Aquaporin 10/AQP10 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 10.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Aquaporin 10

Target: Aquaporin 10 (AQP10)

Alternative Name: AQP10

Background:

Background: AQP10 was identified in human small intestine. This gene encoded a 264-amino-acid protein with high sequence identity with AQP3 (53 % ), 9 (52 %), and 7 (43 %). These AQPs constitute one subfamily of AQP family that is differentiated from the other subfamily of AQP (AQP0, 1, 2, 4, 5, 6, and 8) by sequence homology. Northern blot analysis revealed expression of a 2.3-kb AQP10 transcript in jejunum but not liver. RNase protection analysis detected nearly exclusive expression in duodenum and jejunum. In situ hybridization analysis demonstrated highest expression of AQP10 in absorptive epithelial cells at the tips of villi in the jejunum. SDS-PAGE analysis showed expression of a 28-kD AQP10 protein, similar to its predicted size as well as to that of the other AQPs. Functional analysis indicated that cells expressing AQP10 are permeable to relatively low amounts of water, but, unlike AQP3, AQP7, and AQP9, are not permeable to urea or glycerol.

Gene Full Name: aquaporin 10

Gene ID: 89872

UniProt: Q96PS8