ALOX5AP antibody (Middle Region)
Quick Overview for ALOX5AP antibody (Middle Region) (ABIN7969883)
Target
See all ALOX5AP AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- Middle Region
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Purpose
- Anti-ALOX5AP Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Predicted Reactivity
- identical to the related mouse,rat sequences.
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Characteristics
- Anti-ALOX5AP Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human ALOX5AP, identical to the related mouse and rat sequences.
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
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Alternative Name
- ALOX5AP
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Background
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Background: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene Full Name: arachidonate 5-lipoxygenase activating protein
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Molecular Weight
- 18 kDa
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Gene ID
- 241
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UniProt
- P20292
Target
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