RERE antibody (AA 109-1037) (Biotin)

Catalog No. ABIN7970016

This Rabbit Polyclonal antibody specifically detects RERE in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for RERE antibody (AA 109-1037) (Biotin) (ABIN7970016)

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RERE antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-RERE Antibody (Biotin)

Binding Specificity: AA 109-1037

Purpose: Anti-RERE Antibody Biotin Conjugated

Predicted Reactivity: Human RERE shares 92.4%,92.3% amino acid (aa) sequence identity with mouse,rat RERE,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RERE recombinant protein (Position: D109-H1037). Human RERE shares 92.4% and 92.3% amino acid (aa) sequence identity with mouse and rat RERE, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RERE

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Alternative Name: RERE

Background:

Background: Arginine-glutamic acid dipeptide repeats protein is a protein that in humans is encoded by the RERE gene. This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: arginine-glutamic acid dipeptide repeats

Gene ID: 473

UniProt: Q9P2R6

Pathways: Protein targeting to Nucleus