Aryl Hydrocarbon Receptor antibody (AA 6-842) (APC)

Catalog No. ABIN7970221

The Rabbit Polyclonal anti-Aryl Hydrocarbon Receptor antibody is suitable to detect Aryl Hydrocarbon Receptor in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Aryl Hydrocarbon Receptor antibody (AA 6-842) (APC) (ABIN7970221)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Aryl Hydrocarbon Receptor Antibody (APC)

Binding Specificity: AA 6-842

Purpose: Anti-Aryl hydrocarbon Receptor/AHR Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Aryl hydrocarbon Receptor/AHR recombinant protein (Position: A6-L842).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background:

Background: The aryl hydrocarbon receptor (AhR or AHR or ahr or ahR) is a protein that in humans is encoded by the AHR gene. It is mapped to 7p21.1. The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm, upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.

Gene Full Name: aryl hydrocarbon receptor

Gene ID: 196

UniProt: P35869

Pathways: Regulation of Cell Size